Need to find an alternative to IV Vitamin C. Prices here locally in California are $250 per session, 3X per week, at 16 weeks is about $12,000, which is prohibitive for most people. About the same price, slightly lower, for HBOT. Need to find other ways of offering these benefits
Have you tried fasting, and other free methods to improve health? My pubs have lots of free content with examples of things far more powerful than pharma, and all free.
This response will be unwelcome, I am sure, but as a practitioner one has to be mindful of cherry picking the data. While ketosis does upregulate antioxidant enzymes, this is because fat oxidation inherently produces more reactive oxygen species per unit of energy. The body's antioxidant response is trying to compensate for the higher oxidative load (ie it forces the body to produce more SOD just to cope with the onslaught) and is NOT evidence that ketosis is less oxidatively stressful. The fundamental biochemistry shows that fat oxidation requires more electron transport chain activity and generates more sites for ROS production. Measuring antioxidant upregulation without measuring total ROS production is like measuring how many fire extinguishers a building has without counting how many fires are starting. If one shifts the conversation from "antioxidant responses" to "net oxidative burden calculation" - the whole argument falls apart. when you look at the work of Thomas Seyfried - he has nothing to show, no clinical evidence that doing a ketogenic diet for cancer produces cure.
Simply put if I understand your very detailed argument.
There are no advantages to eating a diet which produces more ketones than eating the typical American diet which is loaded with carbohydrates especially refined carbohydrates. Is this true?
I do not believe a ketogenic-like diet in and of itself in the absence of reasonable supplementation is the correct approach giving that a higher risk of cancer cell production is especially when you add the spike protein factor. Most accept grossly effects of oxidative phosphorylation, damaging the mitochondria. I think the main message that I embrace is a greater balance which moves away from a diet that disproportionately sets the body up for larger levels of ROS production.
I am not speaking about extremes, but I am speaking about shifting the glucose burden versus a shift toward more ketones given the epidemic persistence of two diabetes.
Are there advantages to having more ketones as a source for fuel. Ketone versus glucose? Are you completely disregarding the Warbug effect as bogus?
Again, it appears that you are cautioning about an extreme ketogenic diet rather than the advantages of decreasing glucose levels and increasing healthy fats, adding a multiplicity of antioxidant rich vegetables in the diet.
Please clarify and thank you very much again for your very detailed response.
I have been through 4 rounds of prostate cancer conventional treatment in the last 13 years and just now went from undetectable to off nominal.08 PSA. Conventional therapy is looking like whack-a-mole. This looks promising if I can find medical supervision by a willing provider. Agree on the cost of IV vitamin C, is liposomal C adequate, I can make it myself and begin to flush it digestively after 35 g per day. Thoughts and resources to move forward? Or other similar protocols?
Need to find an alternative to IV Vitamin C. Prices here locally in California are $250 per session, 3X per week, at 16 weeks is about $12,000, which is prohibitive for most people. About the same price, slightly lower, for HBOT. Need to find other ways of offering these benefits
Look into liposomal vitamin C as discussed by Dr. Thomas Levy.
Have you tried fasting, and other free methods to improve health? My pubs have lots of free content with examples of things far more powerful than pharma, and all free.
Wow. This is amazing.
Fasting > Pharma
There's a lot of contradictions here:
Complex III is essential for normal oxidative phosphorylation
Inhibiting Complex III blocks electron flow and reduces ATP production
You cannot restore OxPhos by blocking a critical component of the electron transport chain
Ketogenic metabolism can increase mitochondrial oxidative stress
Higher fat oxidation can lead to increased ROS production
The combination of metabolic stress from fasting + high-fat diet + Complex III inhibition could be particularly problematic
https://pubmed.ncbi.nlm.nih.gov/26661201/#:~:text=Ketones%20decrease%20oxidative%20stress%2C%20increase,diet;%20mitochondria;%20oxidative%20stress.
This response will be unwelcome, I am sure, but as a practitioner one has to be mindful of cherry picking the data. While ketosis does upregulate antioxidant enzymes, this is because fat oxidation inherently produces more reactive oxygen species per unit of energy. The body's antioxidant response is trying to compensate for the higher oxidative load (ie it forces the body to produce more SOD just to cope with the onslaught) and is NOT evidence that ketosis is less oxidatively stressful. The fundamental biochemistry shows that fat oxidation requires more electron transport chain activity and generates more sites for ROS production. Measuring antioxidant upregulation without measuring total ROS production is like measuring how many fire extinguishers a building has without counting how many fires are starting. If one shifts the conversation from "antioxidant responses" to "net oxidative burden calculation" - the whole argument falls apart. when you look at the work of Thomas Seyfried - he has nothing to show, no clinical evidence that doing a ketogenic diet for cancer produces cure.
Simply put if I understand your very detailed argument.
There are no advantages to eating a diet which produces more ketones than eating the typical American diet which is loaded with carbohydrates especially refined carbohydrates. Is this true?
I do not believe a ketogenic-like diet in and of itself in the absence of reasonable supplementation is the correct approach giving that a higher risk of cancer cell production is especially when you add the spike protein factor. Most accept grossly effects of oxidative phosphorylation, damaging the mitochondria. I think the main message that I embrace is a greater balance which moves away from a diet that disproportionately sets the body up for larger levels of ROS production.
I am not speaking about extremes, but I am speaking about shifting the glucose burden versus a shift toward more ketones given the epidemic persistence of two diabetes.
Are there advantages to having more ketones as a source for fuel. Ketone versus glucose? Are you completely disregarding the Warbug effect as bogus?
Again, it appears that you are cautioning about an extreme ketogenic diet rather than the advantages of decreasing glucose levels and increasing healthy fats, adding a multiplicity of antioxidant rich vegetables in the diet.
Please clarify and thank you very much again for your very detailed response.
Are there any studies concerning ivermectin and endometriosis?
How on earth is it possible to buy this or get it sent to Canada ? I’m desperate.
I have been through 4 rounds of prostate cancer conventional treatment in the last 13 years and just now went from undetectable to off nominal.08 PSA. Conventional therapy is looking like whack-a-mole. This looks promising if I can find medical supervision by a willing provider. Agree on the cost of IV vitamin C, is liposomal C adequate, I can make it myself and begin to flush it digestively after 35 g per day. Thoughts and resources to move forward? Or other similar protocols?