Note: this is part two of the Ivermectin and Mebendazole for Cancer case reports series. See the first part and third part of this series.
In this update, we present 13 case testimonials published in July 2025.
Case No.1: 65 year old Florida man with new Prostate Cancer sees improvement after 4 months
Dr William Makis shared on X.com in July 2025:
IVERMECTIN and FENBENDAZOLE Testimonial - 61 year old NC man with Gleason 8 Prostate Cancer has no spread on surgery and drops to Gleason 7, as PSA also drops! Repurposed drugs will often limit the spread of cancer and leave shocking results on pathology. I have many testimonials now of "unexpected" results on pathology after a few months of Ivermectin, Fenbendazole or Mebendazole and I will be posting these in the coming weeks. 61 year old NC man with Gleason 8 Prostate Cancer On Feb.12, 2025 we started:
Ivermectin 1.5mg/kg/day
Fenbendazole 1000mg/day (eventually increased to 2000mg/day after 2 months, after PSA stayed stable)
CBD Oil 100mg/day
Results after 3.5 months:
PSA 6.3 to 4.5
No spread of Cancer
Gleason 8 to Gleason 7
From patient: "Prostate removed - pathology report shows no sign of spread, all contained within the prostate. Gleason score reduced from 4+4 to 3+4" That's a full two degrees less in aggressiveness. The cancer went from 4+4 to 4+3 to 3+4.
Read more: Ivermectin and fenbendazole for prostate cancer case reports (28 cases)
Case No.2: 65 year old Florida man with new Prostate Cancer sees improvement after 4 months
Dr William Makis shared on X/Twitter in July 2025:
IVERMECTIN and FENBENDAZOLE Testimonial - 65 year old Florida man with new Prostate Cancer sees improvement after 4 months We have so many Prostate Cancer successes! 65 year old Florida man with new Prostate Cancer PIRADS-4. In late January 2025 we started:
Ivermectin 1.5mg/kg/day
Fenbendazole 888mg/day
CBD Oil 100mg/day
Results after 4 months:
PIRADS-4 to PIRADS-3 and smaller lesion.
Sometimes we celebrate big successes, sometimes we celebrate small successes. But the reality is that the risk of trying repurposed drugs in Cancer is minimal. And the risk/benefit calculation almost always weighs heavily in the direction of "benefit".
Case No. 3: 63 year Canadian woman with Stage 3 Breast Cancer
Dr. William Makis shared on X (Twitter) in July 2025:
IVERMECTIN and MEBENDAZOLE Testimonial - 63 year Canadian woman with Stage 3 Breast Cancer after 4 months: 91% reduction of breast mass, 100% elimination of large axillary lymph nodes up to 3.6cm We've had so much success with Breast Cancer! But don't tell
@Grok, our favourite Big Pharma AI. They might just unplug Grok, if it ever starts telling the truth... 63 year Canadian woman with Stage 3 Breast Cancer REGIMEN:
Ivermectin 1.5mg/kg/day (December 2024 onwards)
Fenbendazole 900mg/day (Oct.27, 2024 until Feb.28, 2025)
Mebendazole 1000mg/day (March 1, 2025 onwards)
RESULTS:
Breast Mass 6.5x6.2x6.1cm to 3.0x2.6x2.7cm (91% tumor volume reduction)
multiple axillary lymph nodes up to 3.6cm (100% resolved)
"There is interval resolution of Level 1 and Level 2 axillary lymphadenopathy." Thank God she didn't listen to her incompetent Canadian Oncologist who had said: "He informed me that taking Ivermectin would make the chemotherapy ineffective, and if I had a reaction, I could end up in ICU".
Case No. 4: 72 year old woman in Egypt with Stage 4 Breast Cancer and Lung Cancer metastatic to the brain
Dr. William Makis shared on X (Twitter) in July 2025:
IVERMECTIN and MEBENDAZOLE Testimonial - 72 year old woman in Egypt with Stage 4 Breast Cancer and Lung Cancer metastatic to the brain has up to 96% tumor volume reduction Another international cancer success story!
72 year old woman in Egypt with Stage 4 Breast Cancer and Lung Cancer metastatic to the brain.
On April 17, 2025 we started:
Ivermectin 1mg/kg/day
Mebendazole 1000mg/day
CBD Oil 100mg/day
RESULTS after 2 months:
All brain metastases decreased in size.
Right temporal lobe lesion: 27x16mm to 14x10mm = 80% tumor volume reduction.
Left insular lesion 20x16mm to 8x5mm = 96% tumor volume reduction.
"Wanted to share good news of the Brain MRI!"
I love to see brain lesions shrink on Ivermectin and Mebendazole. Mebendazole is the benzimidazole of choice for brain lesions and brain metastases, as it crosses the blood brain barrier well.
Case No. 5: 46 year old Oklahoma man with Squamous Cell Carcinoma of Base of Tongue combines it with Proton Radiation
Dr William Makis shared on X/Twitter in July 2025:
IVERMECTIN, MEBENDAZOLE and FENBENDAZOLE Testimonial - 46 year old Oklahoma man with Squamous Cell Carcinoma of Base of Tongue combines it with Proton Radiation - they have never seen such a case! Another fascinating Cancer Testimonial!
46 year old Oklahoma man with Squamous Cell Carcinoma of Base of Tongue Patient was on:
1. Ivermectin 80mg/day
2. Mebendazole 1500mg/day
3. Fenbendazole 1000mg/day
From the patient:
"let me tell you my base of tongue and neck tumors have shrunk to almost nothing" "I began Proton Radiation Therapy"
"My tolerance of the treatments has been something of a buzz among the Drs and caregivers. I am 21 of 35 treatments in and I can still eat and speak fine, I can even still lead the singing at one of our weekly church services! I have no pain! Minimum skin burn, like a slight sun burn. No thick saliva and no mucositis. Many of the people I have met since we started were in really bad shape by this point and several had to delay or quit treatment due to mucositis and swallowing difficulties"
Despite the chemo and 1500mg Mebendazole, 1000mg Fenbendazole and 80mg Ivermectin daily, my liver numbers have been excellent".
Case No. 6: 74 year old North Carolina woman with new Renal Cell Carcinoma (papillary)
Dr. William Makis shared on X (Twitter) in July 2025:
IVERMECTIN and FENBENDAZOLE Testimonial - 74 year old North Carolina woman with new Renal Cell Carcinoma (papillary) has tumor shrinkage after 4 months Oncologists have no answers for Kidney Cancer but there is hope!
74 year old North Carolina woman with new Renal Cell Carcinoma (papillary) Regimen (started Feb.16, 2025):
Ivermectin 1mg/kg/day
Fenbendazole 1000mg/day
Results after 4 months Left kidney cancer shrunk 1.4x1.7cm to 0.9x1.3cm = 68.4% tumor volume shrinkage.
It’s important to note that neither Radiologists, nor Oncologists do any calculations of tumor volume reduction. This radiologist called a 68% tumor volume reduction “mildly decreased”.
Case No. 7: 44 year old Australian Man with Hepatocellular Carcinoma (HCC)
Dr. William Makis shared on X (Twitter) in July 2025:
Ivermectin and Mebendazole Testimonial - 44 year old Australian Man with Hepatocellular Carcinoma (HCC) reports success after 3 months.
A success story all the way from Australia! I'm actually helping many cancer patients in Communist Australia, where it's much harder to get Ivermectin and Fenbendazole but where there's a will...
44 year old Australian Man with Hepatocellular Carcinoma (HCC) Late Feb 2025 we started:
Ivermectin 1mg/kg/day
Mebendazole 1000mg/day
Melatonin 300mg/day
Results after 3 months: Tumor markers decreased by 25%.
Liver lesion decreased from 37mm to 30mm = 46% tumor volume shrinkage.
CT: "Significant decreased volume and extent of enhancement of the hepatic lesions from prior" From patient: "Looks like I am going in the right direction. Thanks a lot for your help"
HCC is extremely difficult to treat and Oncologists have no answer for it.
Case No. 8: 57 year old Florida man with Stage 4 Rectal Cancer to liver
Dr William Makis shared on X/Twitter in July 2025 (source):
IVERMECTIN and FENBENDAZOLE Testimonial - 57 year old Florida man with Stage 4 Rectal Cancer to liver (post 2 Pfizer COVID-19 Vaccines) reports after 5 months: 100% resolution of liver metastases!!
57 year old Florida man with Stage 4 Rectal Cancer to liver (post 2 Pfizer COVID-19 Vaccines)
In Mid Jan.2025 we started:
Ivermectin 1.5mg/kg/day
Fenbendazole 1000mg/day
CBD Oil 100mg/day
Results (after 5 months)
Liver metastases (largest 4.7cm) resolved completely (100% resolution) !!
From patient: "I am writing to you in utter shock"
"You are an incredible man that is saving lives and giving people hope and courage."
This time we helped out the Cleveland Clinic and Moffitt Cancer Center.
Case No. 9: 74 year old Arizona Man with a 30cm GIST Tumor * (Gastro-Intestinal Stromal Tumor)
*Note: A type of sarcoma, a rare type of cancer that can be difficult to diagnose and treat. GISTs happen most often in the stomach and small intestine.
Dr. William Makis shared on X.com in July 2025:
IVERMECTIN and MEBENDAZOLE Testimonial - 74 year old Arizona Man with a 30cm GIST Tumor reports after 4 months - tumor shrinkage and central necrosis Gastro Intestinal Stromal Tumors are rare tumors (Sarcomas) that can grow to very large sizes! Here is one Cancer success story that we will probably send for publication. 74 year old Arizona Man with a 30cm GIST Tumor.
In early February 2025 we started:
Ivermectin 1.5mg/kg/day
Mebendazole 1500mg/day
Results after 4 months: The tumor had actually shrunk from 30cm to 23cm with decrease in SUVmax from 3.5 to 2.4 and central necrosis, consistent with a dying tumor.
From patient: "We have shrinkage and metabolic dying! I am in tears and we both are very grateful to you and our Oncologist for sharing your wisdom with us and others!"
Case No. 10: 74-yr-old man with Metastatic Prostate Cancer, Liver and Lymph Node Metastases
Published on Fenbendazole Can Cure Cancer (July 2025):
This is the account of a 74-year-old man, 6-ft, 169 pounds, who faced a dire prognosis of terminal, metastatic prostate cancer but charted an unconventional path to remarkable recovery, primarily through the determined use of fenbendazole. His journey told by his daughter TW, underscores a powerful testament to individual agency in the face of seemingly insurmountable odds.
The Onset of Crisis: A Timeline of Decline
TW’s dad’s battle with prostate cancer began in 2019, a diagnosis initially met with surgical removal of the prostate and an “all clear.” However, the reprieve was short-lived. The timeline of his relapse and subsequent crisis unfolded rapidly in 2024:
Early August 2024: Routine blood work delivered alarming news – a PSA of 14.
Mid-August 2024: The situation escalated dramatically. His PSA soared to 51, and asubsequent PET scan revealed the devastating spread: metastases to his liver and lymph nodes.
Late August 2024: Biopsies of both the liver and lymph nodes unequivocally confirmed the recurrence of prostate cancer.
The diagnosis from his oncologist at a leading cancer center (MDA) was grim: Stage 4 metastatic prostate cancer. He was informed that his liver was “completely consumed” and that medical intervention could offer nothing beyond palliative care. The proposed conventional treatment plan comprised hormone therapy (Lupron) followed by chemotherapy, with a stark prognosis of 12-18 months of life remaining.
A Divergent Path: Embracing Fenbendazole
Faced with this bleak outlook, TW’s dad’s made a pivotal decision. In September 2024, he received the initial Lupron shot as prescribed. However, during this consultation, he inquired about the fenbendazole protocol. His MDA oncologist unequivocally stated that if he chose to pursue fenbendazole, he could no longer be seen as a patient. Despite outwardly agreeing to forgo it, TW’s dad’s, resolute in his conviction, returned home and immediately initiated the fenbendazole protocol, choosing not to inform his oncologist.
His self-directed fenbendazole regimen commenced in late August 2024. He began with 222mg of fenbendazole (from Panacur C powder, meticulously weighed) once daily for seven days, quickly increasing to 222mg twice daily (total 444mg fenbendazole per day), taken after breakfast and dinner with peanut butter to aid absorption.
While fenbendazole was the central therapeutic agent, he adopted a comprehensive adjunctive strategy: a ketogenic diet (resulting in a 30-pound weight loss in three months), daily ivermectin (an eraser-sized amount of horse paste), Vitamin D, Serrapeptase, Soursop tea, TUDCA, Lion’s Mane, Onco Pathways 1-4 from UltraBotanica, high-dose intravenous Vitamin C (50-75 grams, three times a week), and monthly three-day fasts (water and bone broth only). Lupron remained the only conventional medical treatment he had ever received.
Immediate Impact and Astounding Turnaround
The effects of fenbendazole were felt almost immediately. Any existing pain and discomfort abated rapidly upon starting the fenbendazole, a profound and immediate improvement in his quality of life. Despite the grave diagnosis, TW’s dad’s reported feeling remarkably well throughout this period, never experiencing debilitating symptoms often associated with advanced cancer.
The true measure of fenbendazole’s efficacy became undeniably clear within three months.
Early November 2024: A follow-up appointment at MDA, initially intended to plan for chemotherapy, delivered astonishing news. A PET scan revealed a 50% reduction in all tumors. His oncologist was, by report, “shocked.”
Bloodwork corroborated this stunning reversal: his PSA, which had peaked at 51 in mid-August, had plummeted to just 2 by early November 2024.
The chemotherapy scheduled for that very day was promptly cancelled in light of these profoundly positive results.
Sustained Progress and Vigilant Management
TW’s dad’s continues his fenbendazole regimen (222mg twice daily, seven days a week) and the supportive protocols. He proactively monitors his liver enzymes (AST/ALT) through independent lab work, as these showed elevation on two occasions initially after starting fenbendazole. There were no adverse side effects attributed to fenbendazole. TW’s dad’s has not, and will not, disclose his fenbendazole use to his MDA oncologist.
His daughter, T.W., reported a further update from a follow-up visit at MDA on January 7, 2025:
His cancer showed an additional 50% decrease from the November scan. This marked a total 75% reduction in all tumors within just five months (August 2024 to January 2025) of commencing the fenbendazole-centric protocol. As of May 2025 there is no evidence of disease as confirmed by PET/CT scans.
TW’s dad’s speculates his cancer may have been linked to a diet high in sugar, processed foods, and carbohydrates, and potentially to COVID-19 vaccinations (two shots and one booster).
When sharing her Dad’s experience, TW said that reactions range from surprise and intrigue, with many requesting his protocol for loved ones, to indignation that such a potentially effective and accessible option is not offered by mainstream oncology.
“My Dad is doing amazing! He is still following the Joe Tippin's protocol and also uses Ivermectin and does high dose 100g Vit C IV's 3 days a week. His liver enzymes have been wonderful with no issues at all. He's stronger and more active now than he's ever been. He still eats all organic, no antibiotic or hormone foods and follows Keto; he even goes to the gym 4 days a week without question. He has zero size effects from any of the cancer or therapies we're doing. His next appt with MD Anderson is June 2025, we use them so we get the PET/CT scans and can track his progress. Here is a spreadsheet I put together showing his progress to date. To this day he has still had no radiation or chemo and doesn't plan to.”
Q: We are getting ready to publish your Dad’s story, did he happen to be taking aspirin in any form while self-treating with fenbendazole?
A: No aspirin.
““He had a follow up on 6/28 and another 30% reduction from last appointment. His cancer has digressed by 80% now overall. His tumors in the lymph nodes and lungs are now completely gone. MD Anderson is still tapping their foreheads asking “are you doing anything besides the lupron shot we gave you?” Of course we say no because Dad wants to still get the quarterly PET scans to track his progress.””
Summary
This Case Report documents the extraordinary turnaround of a 74-year-old man diagnosed in August 2024 with Stage 4 metastatic prostate cancer, with extensive liver and lymph node involvement, and given a palliative prognosis of 12-18 months. Forsaking further conventional treatment beyond an initial Lupron injection, he independently initiated a daily regimen of fenbendazole (444mg total). He experienced an immediate abatement of all pain and discomfort. Within three months, his PSA plummeted from 51 to 2, and imaging confirmed a 50% reduction in all tumors, leading to the cancellation of planned chemotherapy. After five months on fenbendazole, his total tumor burden had decreased by an astounding 75%, now NED in liver at 11 months. This remarkable outcome, primarily attributed by TW’s dad to fenbendazole, underscores the profound anti-cancer effects he experienced with fenbendazole.
Case No. 11: 59 year old Canadian woman with Stage 4 Colon Cancer metastatic to liver and lymph nodes
Dr William Makis shared on X.com in July 2025 (source):
IVERMECTIN and FENBENDAZOLE Testimonial - 59 year old Canadian woman with Stage 4 Colon Cancer metastatic to liver, lymph nodes, reports after 1.5 months Colon Cancer has not been easy to deal with. Some cases respond very well and some don't. We still have a lot of work to do here. STORY: 59 year old Canadian woman with Stage 4 Colon Cancer metastatic to liver, lymph nodes In mid April 2025 we started:
Ivermectin 1.5mg/kg/day
Fenbendazole 1500mg/day
CBD Oil 100mg/day
Results after 1.5 months “aggregate size of her tumors had shrunk in excess of 20%” "Our Oncologist was thrilled..."
Case No. 12: 64 year old Idaho man with Stage 4 NSCLC Lung cancer and Thyroid Cancer
Dr William Makis shared on X.com in July 2025:
IVERMECTIN and FENBENDAZOLE Testimonial - 64 year old Idaho man with Stage 4 NSCLC Lung cancer and Thyroid Cancer reports after 2 months. Many lung cancer cases respond very well to Ivermectin and Fenbendazole. Story: 64 year old Idaho man with Stage 4 NSCLC Lung cancer and history of Thyroid Cancer. We started on April 8:
Ivermectin 1.0mg/kg/day
Fenbendazole 1500mg/day
CBD Oil 100mg/day
Oncologist started chemo
Results after 2 months: Lingular mass 5.3x5.6cm shrunk to 2.5x4.0cm = 76% tumor volume shrinkage (calculations by Grok). You don't see these kinds of results with chemo, the Oncologists themselves admit this, especially when they don't know what the patient is taking.
Case No. 13: 66 year old North Carolina woman with Stage 4 Breast Cancer metastatic to bones
Dr. William Makis shared on X.com in July 2025:
IVERMECTIN and MEBENDAZOLE Testimonial - 66 year old North Carolina woman with Stage 4 Breast Cancer metastatic to bones reports after 1 month (tumor shrinkage by over 50%). WARNING: No chemo involved! I have been inspired by recent Alberta government attacks to increase my testimonial posts. I'm always asked if repurposed drugs like Ivermectin, Fenbendazole and Mebendazole work without chemo.
STORY: 66 year old North Carolina woman with Stage 4 Breast Cancer metastatic to bones On June 25 we started:
Ivermectin 1mg/kg/day
Mebendazole 1000mg/day
CBD Oil 100mg/day
RESULT after 1 month:
"During my visit yesterday...my oncologist examined my breast and was astonished to find the mass had reduced by over 50%. He noted that this result far exceeded his expectations and considered it highly unlikely that hormone therapy alone could act this quickly. He is aware of my use of Ivermectin and Mebendazole and was amazed by the progress"
The Wellness Company's Ivermectin and Mebendazole
Ivermectin and mebendazole, both approved for human use, are now available in the U.S.
Researched and approved by Dr. Peter McCullough.
Prescribed by licensed medical professionals
Compounded and dispensed by a licensed US-based pharmacy
Approved for human use
Where to buy Ivermectin and Mebendazole Formula: Available on The Wellness Company's website. Here is the link: Ivermectin and Mebendazole.
Thank you so much for sharing. 😌
Thank you for sharing this. I have a couple of questions that I hope someone can clarify: Is The Wellness Company, including Dr. McCullough, a paid advertiser or sponsor? And, more importantly, is there any connection between the company or its affiliates and the obstacles Dr. William Makis has reportedly faced in trying to open his HOPE Clinic in Florida?
The world owes Dr. Makis an enormous debt of gratitude for his commitment to helping patients and sharing information make a difference. For those seeking additional information and resources, I strongly encourage people to explore Dr. Makis’ Substack and do their own research. I personally know several people who have sought information through his work and have had positive experiences.
What stands out to me most is Dr. Makis’ integrity and determination. He has continued to advocate for patients despite significant opposition and pressure.
If anyone has the political connections, resources, or financial means to help Dr. Makis get the HOPE Clinic opened in Florida, please consider stepping forward and helping make that happen as soon as possible.
Patients need access to more options, more information, and more people willing to stand up and help. Thank you.